Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, of scores for kidney appearance showed that for 4% H₂ inhalation, morphological lesions were alleviated in about 70% rats of this group, while for 67% H₂ inhalation, the number of improved rats was less (about 55%), but the remission effect…
Read ArticleIn Inflammation in male C57/BL6J mice or RAW264.7 cells was induced with LPS, for which hydrogen was immediately administered until samples were taken, hydrogen alleviated LPS-induced inflammatory infiltration…
Read ArticleIn mice, repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors of mice, assessed by tail suspension…
Read ArticleIn mice, the inhalation of H₂ (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to 70 or 60%, respectively. These preclinical…
Read ArticleIn mice, treatment of ovalbumin-sensitized and challenged mice with hydrogen reversed the energy metabolic pathway switch, and mitigated airway inflammation. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn participants with ISSNHL to receive either H₂ (H₂ group) or air as a placebo (control group) through inhalation combined with the administ, the hearing threshold 3 months…
Read ArticleHydrogen inhalation is associated with a transient rightward shift in prefrontal oxyhemoglobin asymmetry and autonomic modulation. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained…
Read ArticleIn mice, the ulcer size in control mice at 4 days after reperfusion was assigned a value of 100%. * P <.05; ** P <.01; *** P <.001…
Read ArticleIn rats, at 2 hours after fluid resuscitation, blood pressure remained in the normal range and metabolic acidosis was well compensated in the H₂ gas-treated rats, whereas the…
Read ArticleIn Sprague Dawley rats, both profiles of high-dose H₂ breathing reduced the size of the endometrial explants, inhibited cell proliferation, improved superoxide dismutase, glutathione peroxidase, malondialdehyde, and catalase…
Read ArticleCavity flora 16S rRNA gene sequencing showed higher abundance of Ruminococcus and Erysipelotrichaceae flora in the nasal cavity of AR patients than in normal participants, and their abundance…
Read ArticleIn female BALB/c mice, mice in the AR + H₂ group exhibited a 0.60±0.21 g weight gain, which was significantly higher compared with the weight gain in the…
Read ArticleIn mice, hydrogen gas showed protective effects associated with a reduction in inflammatory cell infiltration (neutrophils, macrophages, and lymphocytes), a reduced area of damaged muscle, maintenance of normal…
Read ArticleIn guinea pigs, acute acoustic trauma can be reduced by H₂ when inhaled immediately after impulse noise exposure. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes,…
Read ArticleIn Tissue oxidative stress was analyzed with immunostaining for 8-hydroxy-2'-deoxyguanosine (8-OHdG), hydrogen mitigated such apoptosis at the crypt base, and the LGR5 expression of the tissues was higher…
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